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Summary of content:16 and 17th century，England for 10 years、Plague epidemic in 20 or 30 years leading to the mortality rate in urban areas is as high as 20%，The incidence is sometimes more than twice the mortality rate。The plague causes a short -term economic loss to a country，Because people who can leave the epidemic area have left，Trade activities in the epidemic area are also banned。The role of medicine seems to provide support for the government when panic and fear permeate the entire society，Try to maintain order。But actually，The remaining medical practitioners staying are so poor，And in addition to being able to provide hope，I can hardly provide anything else。Many medical practitioners feel difficult to accept their complete failure，Instead of blame patients and other people's treatment，This may still be obvious today。 

Andrew Wear，Professor Rongxiu, University of London, England。Correspondence address: department of history,University College London, London WC1E 6BT, bet365 Play online games uk. email: a.wear@ucl.ac.uk